Tissue | Cumulative absorbed dose to tissue | |||
---|---|---|---|---|
cGy/MBq | cGy at experimental MTD | |||
177Lu-RS7 | 90Y-RS7 | 177Lu-RS7 at 10.2 MBq | 90Y-RS7 at 3.9 MBq | |
Tumor | 756 | 1,252 | 7,691 | 4,866 |
Liver | 62 | 165 | 636 | 639 |
Spleen | 77 | 111 | 780 | 432 |
Kidney | 58 | 111 | 587 | 432 |
Lungs | 69 | 148 | 702 | 575 |
Stomach | 7 | 19 | 73 | 74 |
Small intestines | 15 | 49 | 156 | 190 |
Large intestines | 12 | 34 | 119 | 130 |
Muscle | 14 | 27 | 141 | 106 |
Blood | 183 | 633 | 1,860 | 2,460 |
Bone marrow | 66 | 228 | 670 | 889 |