TABLE 3

Biodistribution at 3 Hours

Agent%IDPopliteal extraction* (%)
Lymph nodesInjection sites
AxillaryPoplitealIliacFrontRear
99mTc-DTPA-mannosyl-dextran6.1 ± 10.76.1 ± 5.50.18 ± 0.2445.7 ± 8.543.6 ± 8.297.7 ± 2.0
Filtered 99mTc-sulfur colloid6.2 ± 2.26.0 ± 3.32.17 ± 2.7055.5 ± 7.866.9 ± 8.567.4 ± 26.8
nTcDx/nfTxSC7/88/84/47/88/88/8
P0.980.970.190.036<0.0010.007
  • * (%IDpopliteal − %IDiliac) × 100/%IDpopliteal.

  • Number of lymph nodes or injection sites for each agent (99mTc-DTPA-mannosyl-dextran [TcDx] or filtered 99mTc-sulfur colloid [fTcSC] at each time point that satisfied our injection criteria.