TABLE 2

Biodistribution of ^99mTc-HYNIC-IL-8 and ^99mTc-HMPAO-Granulocytes in 2 Groups of Rabbits with Experimental Colitis

Parameter	4 h after injection		P*
Parameter	^99mTc-HYNIC-IL-8 (%ID/g)	^99mTc-HMPAO-granulocytes (%ID/g)	P*
Blood	0.044 ± 0.001	0.30 ± 0.03	<0.007
Small intestine	0.032 ± 0.003	0.024 ± 0.003	<0.06
Nonaffected colon tissue	0.025 ± 0.004	0.023 ± 0.008	<0.70
Affected colon tissue	0.41 ± 0.04	0.091 ± 0.055	<0.007
Feces
Nonaffected colon	0.005 ± 0.001	0.015 ± 0.003	<0.35
Affected colon	0.013 ± 0.002	0.022 ± 0.007	<0.26
Lung	0.27 ± 0.09	0.18 ± 0.01	<0.70
Spleen	0.67 ± 0.22	0.83 ± 0.12	<0.15
Kidney	1.86 ± 0.28	0.20 ± 0.01	<0.007
Liver	0.091 ± 0.005	0.21 ± 0.03	<0.007

↵* Mann–Whitney test: ^99mTc-HYNIC-IL-8 vs. ^99mTc-HMPAO-granulocytes. Level of significance was set at P < 0.05.
Biodistribution of 2 groups of rabbits (5 rabbits per group) is shown at 4 h after injection. Data are expressed as mean ± SEM.