Mean T/NT of Infected/Inflamed Thigh Muscles After Injection of 99mTc-Labeled Compounds
| 99mTc-labeled compound | S. aureus and MRSA | K. pneumoniae | C. albicans | Sterile inflammation | |
|---|---|---|---|---|---|
| LPS | Heat-killed microorganisms | ||||
| UBI 29–41 | 3.3 ± 0.2 (21)* | 2.3 ± 0.1 (21)* | 2.8 ± 0.2 (14)* | 1.4 ± 0.1 (12) | 1.4 ± 0.1 (12) |
| UBI 18–35 | 2.4 ± 0.1 (33)* | 2.7 ± 0.2 (16)* | 2.7 ± 0.3 (8)* | 1.0 ± 0.1 (22) | 1.2 ± 0.1 (18) |
| UBI 31–38 | 3.7 ± 0.4 (6)* | 2.0 ± 0.1 (8)* | ND | 1.1 ± 0.1 (6) | ND |
| hLF 1–11 | 2.5 ± 0.2 (12)* | ND | 3.4 ± 0.3 (8)* | 1.1 ± 0.1 (12) | 1.4 ± 0.1 (6) |
| hLF 4–11 | 1.7 ± 0.2 (6) | ND | ND | 1.6 ± 0.2 (6) | ND |
| hLF 21–31 | 4.1 ± 0.7 (6)* | ND | 2.4 ± 0.4 (6)* | 1.4 ± 0.1 (6) | ND |
| HNP-1–3 | 2.4 ± 0.2 (32)* | 1.9 ± 0.1 (22)* | 3.2 ± 0.5 (6)* | 1.0 ± 0.1 (6) | ND |
| Ciprofloxacin | 1.8 ± 0.1 (6) | 1.7 ± 0.1 (6) | 2.6 ± 0.2 (15)* | 2.0 ± 0.1 (8) | 1.7 ± 0.2 (6) |
| IgG | 2.5 ± 0.2 (31) | 2.0 ± 0.3 (22) | 4.2 ± 0.3 (6)* | 2.1 ± 0.2 (8) | 2.0 ± 0.1 (14) |
↵* T/NT is significantly higher (P < 0.05) than T/NT in mice injected with LPS or heat-killed microorganisms.
ND = not done.
Values are mean ± SEM T/NT observed at 30, 60, and 120 min after injection of tracer. The number of animals is given in parentheses.