TABLE 1

Tissue Uptake of FES for 37-MBq Injection

OrganNo. of studiesC̃ Mean (SD) (kBq-h/g)Organ mass (g)Ã Mean (SD) (MBq-h)
Breast470.7 (0.3)3610.2 (0.1)
Gall Bladder1531.7 (16.8)491.6 (0.8)
Intestines*
 145.8 (7.0)
 214 (28)9.8
 34 plus pooled6.6 (6.4)176 (ULI) + 322 (SmI)3.3 (3.2)
Blood482.0 (0.5)347 (heart contents)0.7 (0.2)
Heart Wall481.8 (0.6)2410.4 (0.1)
Kidneys34.2 (0.7)2481.0 (0.2)
Liver4918.9 (4.8)140026.4 (6.7)
Lungs481.3 (0.5)6510.8 (0.3)
Red Marrow471.2 (0.6)10501.2 (0.6)
Spleen181.1 (0.7)1230.1 (0.1)
Bladder*
 1214.4 (10.1)
 216 (28)18.3
 32 plus pooled15.7 (7.5)1602.5 (1.2)
Uterus*
 134.8 (2.7)
 210 (18)7.6
 33 plus pooled5.5 (2.6)790.4 (0.2)
Remainder50,79358.9 (7.6)
  • * These organs also had additional points from more sparsely sampled TACs. 1 = fully sampled curves; 2 = pooled additional data (parentheses indicate number of points used in curve); 3 = mean of fully sampled curves plus additional value from pooled data. These numbers are used for Table 2.

  • Remainder of body for 56-kg woman.

  • ULI = large intestine; SmI = small intestine.