Organ | Uptake at 4 h after injection* (%ID) | Effective half-life† (h) | Residence time (h) | Absorbed dose (μGy/MBq) |
---|---|---|---|---|
Kidneys | 21.0 ± 5.6‡ | 6.3 ± 0.4 | 1.75 ± 0.40 | 93 ± 24 |
Liver | 12.8 ± 2.2 | 5.5 ± 0.2 | 1.11 ± 0.15 | 17 ± 2 |
RM | 4.2 ± 1.6 | 5.1 ± 0.4 | 0.34 ± 0.11 | 5.5 ± 0.8 |
Spleen | 2.5 ± 1.3 | 5.2 ± 0.7 | 0.17 ± 0.08 | 22 ± 6 |
Testes (n = 6) | 0.51 ± 0.10 | 5.1 ± 0.5 | 0.042 ± 0.009 | 15 ± 3 |
Thyroid | 0.21 ± 0.11 | 4.6 ± 0.5 | 0.016 ± 0.009 | 10 ± 6 |
Urinary bladder§ | 0.13 ± 0.03 | 7.5 ± 2.6 | ||
Remainder | 4.0 ± 0.7 | |||
Total body | 91.0 ± 6 | 5.5 ± 0.2 | 7.5 ± 0.4 |
↵* Uptake values are corrected for physical decay.
↵† Results are from fit with single exponential.
↵‡ Computed as 2× left kidney uptake (10.5% ± 2.8%).
↵§ Dynamic bladder model (16); voiding interval = 4 h; biologic half-life of activity in total body from individual measurements (average, 62 ± 13 h); fraction of activity to urine = 0.75.