TABLE 1.

Dosimetric Data for Intravenously Administered 99mTc-i-AnxV (n = 8)

OrganUptake at 4 h after injection* (%ID)Effective half-life (h)Residence time (h)Absorbed dose (μGy/MBq)
Kidneys21.0  ±  5.66.3  ±  0.41.75  ±  0.4093  ±  24
Liver12.8  ±  2.25.5  ±  0.21.11  ±  0.1517  ±  2
RM4.2  ±  1.65.1  ±  0.40.34  ±  0.115.5  ±  0.8
Spleen2.5  ±  1.35.2  ±  0.70.17  ±  0.0822  ±  6
Testes (n = 6)0.51  ±  0.105.1  ±  0.50.042  ±  0.00915  ±  3
Thyroid0.21  ±  0.114.6  ±  0.50.016  ±  0.00910  ±  6
Urinary bladder§0.13  ±  0.037.5  ±  2.6
Remainder4.0  ±  0.7
Total body91.0  ±  65.5  ±  0.27.5  ±  0.4
  • * Uptake values are corrected for physical decay.

  • Results are from fit with single exponential.

  • Computed as 2× left kidney uptake (10.5% ± 2.8%).

  • § Dynamic bladder model (16); voiding interval = 4 h; biologic half-life of activity in total body from individual measurements (average, 62 ± 13 h); fraction of activity to urine = 0.75.