TABLE 2.

Residence Times

OrganScaling factor*Clearance half-time (h)Residence time (h)Estimated error (%)
Basal ganglia2.771.38 × 10−230
Heart1.101.129.03 × 10−37
Lungs2.001.042.84 × 10−224
Liver0.281.803.59 × 10−215
Spleen0.881.175.62 × 10−310
Kidney0.382.171.17 × 10−216
Cortical bone0.441.646.43 × 10−213
Trabecular bone0.441.646.43 × 10−213
Muscle0.621.674.69 × 10−18
Testes0.041.971.73 × 10−314
Blood0.651.641.45 × 10−15
Brain1.007.95 × 10−220
Total body1.73 × 1002.6
  • * Empirically derived factor used to match rat and monkey data.

  • Basal ganglia residence time was not included in calculation of total body residence time.