TABLE 2.

Measurements of Median Po₂ by Eppendorf Microelectrodes and Retention of Hypoxic Markers, Gb-d-IAZGP and [^99mTc]HL-91, in Same Dunning R3327-AT Tumors 6 Hours After Administration to Tumor-Bearing Animals

Rat no.	Tumor weight (g)	Median Po₂ (mm Hg)	Gb-d-IAZGP			[^99mTc]HL-91
Rat no.	Tumor weight (g)	Median Po₂ (mm Hg)	%ID/g*	T/B	T/M	%ID/g*	T/B	T/M
1	9.7	2.9 (114*)	0.057	3.3	3.9	0.091	1.5	5.0
2	8.0	2.9 (84)	0.067	3.5	4.9	0.089	1.7	6.8
3	8.9	3.8 (92)	0.082	3.6	4.0	0.134	1.7	6.8
4	9.2	8.9 (105)	0.054	2.5	4.5	0.080	1.3	4.9
5	9.2	5.2 (76)	0.070	3.4	4.1	0.108	1.5	5.5
6	8.4	4.6 (105)	0.063	2.9	3.5	0.138	1.6	7.1
7	5.2	6.2 (88)	0.072	3.4	4.8	0.131	1.6	7.0
8	5.4	6.5 (102)	0.079	3.8	4.8	0.125	1.6	7.1
9	6.0	7.1 (101)	0.074	3.4	3.9	0.135	1.6	7.1
10	7.9	2.8 (104)	0.082	3.5	4.3	0.149	1.7	7.0
11	5.2	4.6 (104)	0.083	3.4	3.6	0.147	1.7	7.4
12	11.8	4.9 (97)	0.078	3.4	4.6	0.109	1.6	6.0
13	6.0	3.7 (106)	0.071	3.2	4.5	0.105	1.5	6.4
14	7.6	3.2 (103)	0.063	2.8	3.6	0.077	1.2	5.4
15	8.0	6.7 (100)	0.075	4.2	5.0	0.109	1.9	7.3
16	7.3	15.4 (119)	0.038	3.0	5.2	0.106	1.7	7.1
17	8.5	4.6 (111)	0.086	4.6	5.4	0.095	2.0	7.6
18	8.1	2.9 (115)	0.071	3.9	5.0	0.098	1.5	5.9
19	6.9	4.7 (85)	0.075	4.4	5.5	0.110	1.9	7.6
20	4.6	3.6 (105)	0.084	3.6	3.9	0.146	1.8	7.1
21	6.0	6.8 (121)	0.056	2.9	3.1	0.091	1.2	5.3
22	13.1	4.1 (102)	0.073	3.3	3.9	0.106	1.6	5.6
23	5.2	3.6 (99)	0.064	3.9	4.3	0.100	1.7	6.9
24	5.6	3.7 (92)	0.067	3.2	3.8	0.107	1.5	7.2
25	7.3	3.5 (109)	0.076	3.1	3.5	0.095	1.5	6.7
26	12.8	4.5 (105)	0.067	3.2	3.2	0.106	1.7	5.6
Mean	7.8	5.1 (102)	0.070	3.4	4.3	0.111	1.6	6.5
SE	0.45	0.51 (2.1)	0.002	0.09	0.13	0.004	0.04	0.17

↵* Number of spatially distinct measurements of tumor Po₂ used to define the median value.