TABLE 2.

T1/2 of DTPA in 14 Irradiated Animals

GroupBaseline (min)After irradiation (min)
Day 12Day 14P*
Group A (without surfactant inhalation)
 Nonirradiated lungs (n = 7)21.8 ± 7.025.6 ± 6.0†26.9 ± 4.2†NS
 Irradiated lungs (n = 7)22.4 ± 5.529.3 ± 5.5‡32.0 ± 4.8§<0.05
Group B (surfactant inhalation)
 Nonirradiated lungs (n = 7)25.4 ± 3.324.2 ± 5.0†37.2 ± 6.6∥<0.01
(surfactant inhalation)
 Irradiated lungs (n = 7)24.6 ± 3.129.0 ± 5.0‡36.3 ± 6.0§<0.01
(surfactant inhalation)

  • ↵* Day 12 vs. day 14.

  • ↵† P = NS vs. baseline.

  • ↵‡ P < 0.05 vs. baseline.

  • ↵§ P < 0.01 vs. baseline.

  • ∥ P < 0.001 vs. baseline.

  • NS = not significant.