Radioactivity in CA20948 Rat Tumors
| Parameter | Time (h) | Tumor (g) |
|---|---|---|
| Radioactivity* (%IA/g) | ||
| 0.9 ± 0.1 | 1 | |
| 0.8 ± 0.1 | 4 | |
| 0.75 ± 0.1 | 24 | |
| 0.4 ± 0.05 | 48 | |
| 0.2 ± 0.03 | 72 | |
| Absorbed dose | ||
| Per injected activity (mGy/MBq) | ||
| 130 | 1 | |
| 160 | 10 | |
| After 370 MBq [90Y-DOTA0,Tyr3]octreotide (Gy) | ||
| 48 | 1 | |
| 60 | 10 |
↵* Percentage of injected activity per gram of tumor (mean ± SD) at various times after injection of [90Y-DOTA0,Tyr3]octreotide (3 MBq coupled to 12 μg); n ≥ 3 in each group.