TABLE 1.

Labeling Efficiencies and RBFs of Various 99mTc-HYNIC-IL-8 and 99mTc-HYNIC-Lysozyme Preparations

ProteinProtein:S-HYNIC*Reaction time (min)Labeling efficiency (%)RBF (%)
IL-81:131565
IL-81:1608731
IL-81:2609424
IL-81:332065
IL-81:3107137
IL-81:3308330
IL-81:3609521
IL-81:10609716
Lysozyme1:3369ND
Lysozyme1:31090ND
Lysozyme1:33095ND
  • * Molar conjugation ratio.

  • For determination of labeling efficiencies, 5 μg HYNIC-conjugated protein were used with 20–30 MBq 99mTc.

  • ND = not determined.