TABLE 3

Radiation Absorbed Dose Estimates (mGy/MBq) for 99mTc-RP527

Target organAverage ± SD
Adrenals2.27 × 10−3 ± 3.55 × 10−4
Brain1.23 × 10−3 ± 1.84 × 10−4
Gallbladder wall1.69 × 10−2 ± 4.32 × 10−3
Lower large intestinal wall7.27 × 10−3 ± 8.68 × 10−4
Small intestine4.53 × 10−3 ± 5.98 × 10−4
Stomach2.12 × 10−3 ± 3.20 × 10−4
Upper large intestinal wall5.46 × 10−3 ± 9.65 × 10−4
Heart wall2.64 × 10−3 ± 5.75 × 10−4
Kidneys2.17 × 10−3 ± 3.04 × 10−4
Liver4.79 × 10−3 ± 1.13 × 10−3
Lungs1.71 × 10−3 ± 3.23 × 10−4
Muscle2.40 × 10−3 ± 2.73 × 10−4
Pancreas2.57 × 10−3 ± 3.86 × 10−4
Red marrow2.18 × 10−3 ± 2.68 × 10−4
Bone surfaces3.46 × 10−3 ± 4.07 × 10−4
Skin1.25 × 10−3 ± 1.47 × 10−4
Spleen1.80 × 10−3 ± 2.74 × 10−4
Thymus1.56 × 10−3 ± 2.49 × 10−4
Thyroid8.07 × 10−3 ± 3.90 × 10−3
Urinary bladder wall9.63 × 10−2 ± 1.16 × 10−2
Uterus*1.08 × 10−2 ± 1.15 × 10−3
Testes1.23 × 10−2 ± 2.70 × 10−3
Ovaries*6.75 × 10−3 ± 5.17 × 10−4
Breasts*9.59 × 10−4 ± 2.28 × 10−4
Total body2.54 × 10−3 ± 3.17 × 10−4
Effective dose equivalent1.13 × 10−2 ± 1.12 × 10−3
Effective dose9.53 × 10−3 ± 1.06 × 10−3
  • * n = 3 women.

  • n = 3 men.

  • Units of effective dose equivalent and effective dose are mSv/MBq.