TABLE 2

Biodistribution of [¹⁸F]FHBG in Tumor-Bearing Mice at 5 Hours

Tissue	Nontransduced tumor model		Transduced tumor model
Tissue	%ID/g	Tumor-to-tissue ratio	%ID/g	Tumor-to-tissue ratio
Blood	0.017 ± 0.001	1.58 ± 0.14	0.017 ± 0.001	20.71 ± 1.06
Skin	0.026 ± 0.001	1.05 ± 0.07	0.030 ± 0.001	11.52 ± 0.62
Muscle	0.017 ± 0.001	1.64 ± 0.12	0.022 ± 0.003	22.23 ± 2.41
Bone	0.225 ± 0.015	0.13 ± 0.01	0.220 ± 0.015	1.71 ± 0.15
Heart	0.020 ± 0.001	1.48 ± 0.15	0.023 ± 0.001	15.74 ± 0.99
Lung	0.031 ± 0.002	0.89 ± 0.06	0.022 ± 0.001	15.73 ± 0.93
Liver	0.047 ± 0.002	0.54 ± 0.02	0.034 ± 0.002	11.23 ± 1.01
Spleen	0.050 ± 0.003	0.55 ± 0.04	0.043 ± 0.003	9.08 ± 0.99
Pancreas	0.028 ± 0.003	1.46 ± 0.28	0.029 ± 0.001	11.49 ± 0.51
Stomach	0.050 ± 0.003	0.84 ± 0.08	0.030 ± 0.001	11.51 ± 0.68
Intestine	0.064 ± 0.005	0.47 ± 0.05	0.058 ± 0.002	5.87 ± 0.27
Kidney	0.054 ± 0.002	0.49 ± 0.03	0.048 ± 0.005	8.86 ± 1.11
Tumor	0.025 ± 0.010		0.335 ± 0.070*

↵* P < 0.001 compared with nontransduced tumor (Student t test on paired samples).
Data are mean ± SEM of 5 animals.