Cellular Accumulation of 99mTc-Labeled Antisense and Sense DNA with Different Dosages of Unlabeled DNA in 2 × 105 Cells
| Unlabeled DNA dosage (ng/mL) | Final DNA concentration (nmol/L) | % Uptake* | P | |
|---|---|---|---|---|
| Antisense DNA | Sense DNA | |||
| 20 | 6.9 | 3.7 ± 0.20 | 2.8 ± 0.3 | 0.009 |
| 36 | 9.6 | 3.2 ± 0.20 | 2.3 ± 0.2 | 0.001 |
| 175 | 33.4 | 1.4 ± 0.10 | 1.5 ± 0.2 | 0.34 (NS) |
| 333 | 60.6 | 1.2 ± 0.05 | 1.0 ± 0.1 | 0.08 (NS) |
| 625 | 100.0 | 1.1 ± 0.06 | 1.1 ± 0.6 | 0.49 (NS) |
↵* Data are presented as mean ± SD (n = 4).
NS = not significant (Student t test, with P < 0.05 considered statistically significant).