Results of Retrospective Analysis of Abnormal MAG3-F0 Studies in Comparison with DMSA (Paired Studies) and Follow-Up Studies
| Patients | MAG3-F0 results | Defect on DMSA | Reflux on cystography | Complete resolution on follow-up studies | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2-min image | 20-min image | Dilated calyx | |||||||||||
| Defect | Hypo | Hyper* | Equal† | Defect | Yes | No | Yes | No | Yes | No | Yes | No | |
| All (n = 36) | 30 | 6 | 21 | 8 | 7‡ | 5‡ | 31 | — | — | 9 | 22 | 6 | 10§ |
| Those with paired studies (n = 28) | 24 | 4 | 15 | 7 | 6 | 4 | 24 | 24 | 4‖ | 9 | 19 | 5 | 9 |
↵* Areas with early depressed or absent activity with delayed retention.
↵† Areas of early decreased or absent activity with delayed normalization.
↵‡ Five of 7 kidneys with fixed defect were associated with dilated calyx (scars?).
↵§ Follow-up studies were available for 16 patients. All patients without resolution had fixed defects on follow-up studies; of them, 7 had fixed defects during APN and 3 had regional parenchymal dysfunction. Seven had dilated calyces, 5 unchanged from acute phase and 2 with previous regional parenchymal dysfunction. Three patients had fixed defects without dilated calyx, 2 unchanged from acute phase and 1 with previous regional parenchymal dysfunction. It appears that fixed defects in acute phase have either worse prognosis for recovery than regional dysfunction or may represent preexistent scars.
↵‖ Of 4 patients without DMSA defects, 1 showed fixed defect on MAG, and 3 showed small area of early decreased activity, with delayed hyperactivity.
Defect = focus of no activity; hypo = focus of decreased activity; hyper = focus of increased activity; equal = activity equal to that of rest of kidney.