TABLE 3.

Contrast and Semiquantitative Results for UAC and NUAC Methods with Three Different Transmission Isotopes

Transmission isotope		^99mTc-T3E3	^99mTc-T1E2	^99mTc-T1E2	²⁰¹Tl	²⁰¹Tl	¹⁵³Gd	—	—	^99mTc-T3E3	²⁰¹Tl	¹⁵³Gd
Emission Transmission		FBP Chang*	FBP Chang	FBP Chang	FBP Chang	FBP Chang	FBP Chang	FBP Sorenson†	FBP Sorenson + head support	OSEM OSEM	OSEM OSEM	OSEM OSEM
TEW scatter correction		Yes	Yes	No E scatter	Yes	No T scatter	Yes	Yes	Yes	Yes	Yes	Yes
Contrast (gray:white)		3.66	3.28	2.28	3.63	3.38	3.58	3.01	3.12	3.79	3.61	3.89

VOI‡	VOI size§
Cortex
Frontal L	1483	100.2	94.8	93.6	100.5	102.9	98.6	102.4	98.3	104.2	104.6	98.8
Frontal R	1517	102.6	103.9	101.7	108.5	112.2	106.8	117.1	113.8	107.5	106.1	106.3
Temporal L	593	108.3	106.6	105.0	107.5	108.2	103.8	98.1	98.4	106.6	104.5	110.9
Temporal R	592	109.4	111.7	109.1	107.3	106.4	110.2	102.5	104.5	100.5	108.4	102.7
Sensorimotor L	254	106.0	99.2	100.4	102.6	101.2	101.9	89.3	88.5	101.4	110.0	111.3
Sensorimotor R	260	110.9	112.8	111.8	106.7	105.4	113.7	106.5	106.5	107.5	118.5	110.1
Parietal L	425	105.1	101.5	100.6	100.0	100.4	102.5	95.4	96.0	101.5	102.2	103.9
Parietal R	425	105.3	105.4	104.7	98.3	98.2	113.4	98.7	99.2	100.5	107.8	102.4
Occipital L	591	94.6	94.2	94.4	91.4	94.2	97.3	96.3	98.6	97.9	95.0	95.2
Occipital R	576	88.5	87.6	89.6	84.7	87.1	89.5	86.8	87.6	87.9	86.2	86.4
Subcortical
Mediotemporal L	177	87.6	93.2	97.7	87.3	80.8	85.0	86.7	90.1	94.8	84.5	90.3
Mediotemporal R	166	91.1	84.5	90.9	94.2	84.8	92.7	83.0	87.1	82.9	94.3	85.6
Striatal L	181	101.5	103.4	108.1	105.5	96.2	98.9	102.4	106.9	103	100.5	104.7
Striatal R	176	106.3	108.3	112.1	109.5	98.0	103.1	106.7	112.6	104	106.1	111.3
Central
Thalamus L	118	92.1	87.2	95.0	90.4	76.5	87.0	85.3	91.2	85.8	82.3	96.5
Thalamus R	114	88.3	82.5	91.3	96.0	81.0	85.0	83.0	89.5	89	86.1	87.9
Pons	130	103.6	109.6	111.0	115.3	101.8	109.0	95.6	98.0	104	103.6	113.9
Cerebellum
Cerebellum L	829	93.9	95.3	97.4	95.4	95.8	88.9	95.9	97.9	97.5	93.2	96.7
Cerebellum R	767	92.1	93.0	93.5	91.9	91.4	95.2	93.1	94.5	89.2	90.0	93.3

↵* Iterative Chang, one iteration.
↵† μ_eff = 0.105 per cm; μ_{head holder} = 0.282 per cm.
↵‡ Normalization to total VOI counts.
↵§ In voxels of 3.59 × 3.59 × 3.59 mm³.
T3E3 = sequential transmission and emission on all three camera heads; T1E2 = simultaneous transmission and emission; E = emission; T = transmission.