Results of Nonirradiated Bone Marrow Specimen from Irradiated Groups Compared with Sham-Irradiated Group
| Parameter | Nonsham-irradiated day 18, n = 4 | Nonirradiated marrow from irradiated groups | ||
|---|---|---|---|---|
| Day 1, n = 3 | Day 9, n = 3 | Day 18, n = 3 | ||
| Total granulocytic cells* (%) | 34.2 ± 3.86 | 33.1 ± 2.52 | 43.9 ± 1.68 | 33.6 ± 4.30 |
| Myeloblast | 0.1 ± 0.11 | 0.1 ± 0.23 | 0.3 ± 0.23 | 0.0 ± 0.00 |
| Promyelocyte | 0.5 ± 0.30 | 1.0 ± 0.09 | 0.9 ± 0.42 | 0.1 ± 0.11 |
| Myelocyte neutrophil | 1.2 ± 0.52 | 1.9 ± 0.70 | 2.2 ± 0.90 | 2.0 ± 0.78 |
| Metamyelocyte neutrophil | 4.3 ± 1.67 | 4.7 ± 1.54 | 4.1 ± 1.37 | 5.2 ± 0.91 |
| Band neutrophil | 9.5 ± 2.64 | 10.0 ± 0.92 | 10.1 ± 3.17 | 10.8 ± 3.59 |
| Segmented neutrophil | 13.0 ± 2.57 | 10.6 ± 1.59 | 18.7 ± 4.99 | 12.2 ± 0.95 |
| Eosinophil | 4.9 ± 1.44 | 4.1 ± 0.34 | 6.9 ± 1.40 | 3.1 ± 0.82 |
| Basophil | 0.7 ± 0.50 | 0.2 ± 0.00 | 0.4 ± 0.18 | 0.1 ± 0.11 |
| Myeloid mitotic figures | 0.0 ± 0.00 | 0.3 ± 0.21 | 0.3 ± 0.23 | 0.2 ± 0.21 |
| Atypical myeloid cells | 0.0 ± 0.00 | 0.0 ± 0.00 | 0.0 ± 0.00 | 0.0 ± 0.00 |
| Total erythroid cells* (%) | 27.3 ± 8.36 | 27.3 ± 7.83 | 34.0 ± 8.19 | 29.3 ± 6.95 |
| Rubriblast | 0.0 ± 0.10 | 0.1 ± 0.11 | 0.2 ± 0.43 | 0.1 ± 0.11 |
| Prorubicyte | 0.9 ± 0.63 | 0.4 ± 0.52 | 1.0 ± 0.16 | 0.7 ± 0.19 |
| Rubricyte, basophilic | 17.7 ± 5.51 | 15.1 ± 3.01 | 24.3 ± 5.17 | 21.5 ± 7.60 |
| Rubricyte, polychromatophilic | 7.5 ± 3.22 | 9.8 ± 3.62 | 7.0 ± 2.45 | 6.4 ± 1.39 |
| Metarubricyte | 1.0 ± 0.61 | 1.7 ± 1.45 | 1.1 ± 0.25 | 0.5 ± 0.22 |
| Erythroid mitotic figures | 0.2 ± 0.16 | 0.2 ± 0.20 | 0.4 ± 0.31 | 0.1 ± 0.11 |
| Lymphoid* (%) | 37.0 ± 4.40 | 38.0 ± 6.82 | 20.4 ± 6.75 | 35.7 ± 3.15 |
| Monocyte* (%) | 0.6 ± 0.29 | 0.4 ± 0.28 | 1.0 ± 0.69 | 0.6 ± 0.31 |
| Plasma cell* (%) | 0.3 ± 0.19 | 0.7 ± 0.30 | 0.6 ± 0.40 | 0.7 ± 0.22 |
| Mast cell* (%) | 0.5 ± 0.35 | 0.5 ± 0.30 | 0.1 ± 0.23 | 0.1 ± 0.11 |
| Lymphoid mitotic figures* (%) | 0.0 ± 0.00 | 0.0 ± 0.00 | 0.0 ± 0.00 | 0.0 ± 0.00 |
| M/E*† | 1.4 ± 0.69 | 1.3 ± 0.52 | 1.4 ± 0.42 | 1.2 ± 0.46 |
| Degenerative cells‡ (%) | 9–19 | <20 | 18–20 | <20 |
| Megakaryocyte | Adequate | No change | No change | No change |
| Overall cellularity | Same as sham group | Same as sham group | Same as sham group | |