Accuracy of PET in Differentiation of Radiation Injury from Tumor Recurrence
| Study | n | Pathology | Sensitivity | Specificity | PPV | NPV |
|---|---|---|---|---|---|---|
| Patronas et al. (25) | 5 | Low-grade glioma | 100 | 100 | ||
| Doyle et al. (26) | 9 | High-grade glioma | 100 | 100 | ||
| Di Chiro et al. (17) | 95 | Glioma + metastases | 100 | 100 | ||
| Valk et al. (24) | 38 | Glioma | 81 | 88 | 79 | 89 |
| Janus et al. (18) | 20 | Glioma | 83 | 63 | 77 | 71 |
| Davis et al. (12) | 35 | Glioma, lymphoma metastases | 83 | No data | ||
| Kahn et al. (28) | 19 | Glioma (n = 17), other (n = 2) | 81 | 40 | ||
| Kim et al. (27) | 33 | Glioma + metastases | 80 | 94 | 92 | 85 |
| Ricci et al. (21) | 31 | Glioma | 86 | 56 | 80 | 46 |
PPV, positive predictive values; NPV, negative predictive values.