Six Formulations of Standard [15O]Water Blood Flow Model
| Model | Fixed parameters | Free parameters |
|---|---|---|
| 1a | α = 1.0, Va = 0 | f, Vd |
| 1b | α = 1.0 | f, Vd, Va |
| 2a | Vd = 0.91 mL/g, Va = 0 | f, α |
| 2b | Vd = 0.91 mL/g | f, α, Va |
| 3a | α = 1.0, Vd = 0.91 mL/g, Va = 0 | f |
| 3b | α = 1.0, Vd = 0.91 mL/g | f, Va |
During fitting procedure, fixed parameters were held at stated values and free parameters were allowed to vary.