Characteristics of ZES Patients
| Characteristic | No. of patients |
|---|---|
| Total no. of patients | 162 |
| Age (y) | |
| Mean ± SEM | 54 ± 1 |
| Range | 19–80 |
| No. of men | 92 (57) |
| MEN-1 present | 39 (24) |
| Other endocrine tumors present (besides gastrinomas) | |
| Parathyroid only | 19 (49) |
| Pituitary only | 1 (3) |
| Parathyroid and pituitary | 12 (31) |
| Parathyroid and thymic carcinoid | 3 (8) |
| Parathyroid, pituitary, and bronchial carcinoid | 4 (10) |
| Fasting gastrin level (pg/mL) | |
| Mean ± SEM | 6,100 ± 2,648 |
| Range | 21–380,000 |
| Basal acid output (mEq/h)* | |
| Mean ± SEM | 30 ± 2 |
| Range | 0–144 |
| Maximal acid output (mEq/h)* | |
| Mean ± SEM | 55 ± 3 |
| Range | 1–155 |
| Evaluation status† | |
| Initial | 46 (28) |
| Follow-up | 116 (72) |
| Disease duration (y)‡ | |
| Mean ± SEM | 14 ± 1 |
| Range | 0.33–42 |
↵* Basal and maximal acid outputs are most recent values.
↵† Evaluation status refers to whether patient was undergoing initial evaluation of gastrinoma location and extent or had undergone previous initial evaluation and was now being evaluated during follow-up visit.
↵‡ Disease duration was time from onset of disease to time of this study.
Normal value for fasting serum gastrin level is <200 pg/mL. Upper limit of normal for basal and maximal acid output in men is <10.5 and 48 mEq/h, respectively; in women, <5.6 and 30 mEq/h, respectively (40). Values in parentheses are percentages.