Patient Characteristics at Baseline with PFT and CT Findings, n = 45
| Characteristic | Value |
|---|---|
| Clinical data* | |
| Age (y) | 58.9 ± 8.9 |
| Female | 33 (73) |
| Male | 12 (27) |
| PFT† | |
| Predicted FVC (%) | 70 (59–86.5) |
| Predicted FEV1 (%) | 667 (57.5–84) |
| KCO (min−1) | 66 (30.5–85)‡ |
| TLCO (mmol min−1 kPa−1) | 41 (25–57)‡ |
| Autoantibodies* | |
| Antiscleroderma-70 | 19 (42) |
| Anticentromere antibody | 4 (9) |
| Anti-RNA-polymerase III | 2 (4) |
| Other§ | 9 (20) |
| No specific antibodies | 10 (22) |
| CT pattern* | |
| NSIP | 42 (93) |
| UIP | 3 (7) |
↵* Continuous variables are expressed as mean ± SD. Qualitative variables are expressed as number with percentages in parentheses.
↵† Data expressed as median with interquartile range in parentheses.
↵‡ n = 35; 10 patients were unable to complete TLCO and KCO tests.
↵§ Includes U1 ribonucleoprotein and rare antinuclear antibodies.
NSIP = nonspecific interstitial pneumonia; UIP = usual interstitial pneumonia.