TABLE 1.

%ID/g of Kidney Tissue Obtained from SPECT/CT Images of Male Wistar Rats After [177Lu]Lu-DOTATOC Coinjection and Changes Relative to 0.9% NaCl

Comedication0.5 h1 h4 h8 h24 h
0.9% NaCl13.3 (8.4)12.2 (8.3)2.7 (0.0)2.7 (0.0)2.4 (0.1)
200 mg/mL Arg-Lys12.0 (1.6)12.1 (3.6)2.1 (0.5)2.0 (0.4)1.9 (0.4)
200 mg/mL PAH6.6 (2.3)6.6 (2.8)1.4 (0.2)1.2 (0.1)1.2 (0.0)
Relative to 0.9% NaCl
 Arg-Lys−10−1−22−26−21
 PAH−50−46−48−56−50

  • PAH = paraaminohippurate.

  • Values are presented as mean %ID/g with SD in parentheses or as percentages.