TABLE 1.

Projected Human Absorbed Doses (mSv/MBq) of [225Ac]Ac-Macropa-N4MU01

OrganAbsorbed dose* (mSv/MBq)
Adrenal gland8.59 × 10−1
Brain7.03 × 100
Breast1.29 × 10−1
Esophagus4.33 × 10−1
Left colon1.13 × 100
Small intestine1.29 × 100
Stomach6.57 × 10−1
Rectum4.37 × 10−2
Heart wall2.01 × 102
Kidneys3.43 × 102
Liver3.02 × 102
Lungs5.08 × 102
Ovaries5.76 × 10−2
Pancreas6.81 × 101
Red marrow1.52 × 10−1
Spleen3.73 × 102
Thymus4.69 × 10−1
Bladder3.10 × 10−1
Uterus6.64 × 10−2
Total body1.89 × 101
Effective dose8.24 × 101
  • * For administration in females.