TABLE 2.

Comparison of TIAC and TIAC Uncertainty Estimates Obtained with MIRDfit, NUKFIT, and SAAM II for 18F-FDG

TIAC ± SD [h]
Source regionFit functionSAAM IINUKFITMIRDfit
Heart wallMonoexponential (physical decay)0.051 ± 0.0090.051 ± 0.0050.051 ± 0.009
BrainBiexponential (uptake and clearance)0.34 ± 0.020.37 ± 0.040.34 ± 0.03
LiverBiexponential (rapid clearance and physical decay)0.143 ± 0.0080.143 ± 0.0100.143 ± 0.008
KidneysBiexponential (rapid clearance and physical decay)0.042 ± 0.0040.042 ± 0.0050.042 ± 0.004