PET and Immunohistochemistry Scores in Pilot Imaging Immunohistochemistry Correlation Study
| Immunohistochemistry score | PET SUV | ||||||
|---|---|---|---|---|---|---|---|
| Case | Site of mPCa biopsy | Reason or choice for site of biopsy | Lesion size (cm2) | FAP | PSMA | FAPi SUVmax | PSMA SUVmax |
| 1 | Iliac crest, acetabulum | Singular FAPi-positive lesion after 223Ra-dichloride | Diffuse, ca. 1.9 × 1.7 on FAPi PET | 20 | 270 | 14.3 | 29.8 |
| 2 | Spine, posterior element T4 | Suspected recurrence on bone scan | 3.4 × 2.7 | 40 | 120 | 8.5 | 10.4 |
| 3 | Retroperitoneal lymph node | Assess for pathologic transformation, obtain tissue for sequencing | 4.2 × 2.5 | 40 | 140 | 10.6 | 18.5 |
| 4 | Retroperitoneal lymph node | Suspicion of second malignancy in kidney | 1.0 × 0.6 | 2 | 180 | 3.0 | 8.9 |
PSA = prostate-specific antigen.