TABLE 3.

Median Survival After Inoculation and Statistical Analysis of PDX2494 on Defined Therapeutic Regimen

ParameterVehicleConventionalPretargeting lowPretargeting highTetrazine alone
Median survival (d)69.571.5738480
P value
 VehicleNS (0.5552)NS (0.2909)0.0005*NS (0.0742)
 ConventionalND0.0051†ND
 Pretargeting low0.0096†ND
 Pretargeting highNS (0.0641)
 Tetrazine alone

  • ↵* P ≤ 0.001.

  • ↵† P ≤ 0.01.

  • NS = nonsignificant; ND = not determined.

  • P values were determined using log-rank Mantel–Cox test.