Uncorrected (PET) and PVE-Corrected Counts Derived from StepBrain PET (GM Counts Averaged over GM Regions of Interest)
Compartment | Target | PET | Rousset | Meltzer | Muller- Gartner CS | PVEOUT | Muller- Gartner RO |
---|---|---|---|---|---|---|---|
GM | 45.53 | 31.64 ± 1.98 | 45.97 ± 1.45 | 43.30 ± 1.42 | 46.00 ± 1.16 | 46.36 ± 1.10 | 45.98 ± 1.16 |
WM | 16.01 | 16.88 | 16.98 | 21.25 | 16.86 | 16.86 | 16.93 |
Striatum | 43.76 | 25.80 | 43.51 | 38.35 | 43.72 | 48.27 | 43.67 |
Counts (kBq/mL) measured in GM regions of interest, WM, and striatum compartments are reported both uncorrected (PET) and PVE-corrected using methods proposed by Meltzer, Rousset, Alfano (PVEOUT), and Muller-Gartner with WM activity measured over Centrum Semiovale (Mull-Gart CS) or according to Rousset (Mull-Gart RO), as implemented in PVELab (17), along with true concentrations (Target).