In Vivo Characterization of [177Lu]Lu-Gemini and Calculated Mouse Dosimetry for Kidney, Blood, and Bone Marrow
| DOTA-radiohapten | Blood half-life (min) | Whole-body half-life (min) | Kidney uptake 3 h after injection (%IA/g) | Kidney dosimetry (mGy/MBq) | Blood dosimetry (mGy/MBq) | Bone marrow dosimetry (mGy/MBq) |
|---|---|---|---|---|---|---|
| [177Lu]Lu-Gemini | 10.12 | 29.06 | 0.57 ± 0.29 | 100.88 | 0.97 | 0.35 |
| [177Lu]Lu-DOTA-Bn | 11.94 | 27.46 | 0.59 ± 0.45 | 104.78 | 1.06 | 0.38 |
For comparison, [177Lu]Lu-DOTA-Bn was investigated using the identical protocol.