Patient Characteristics (n = 852)
| Characteristic | n | % |
|---|---|---|
| Male | 695 | 82 |
| Median age ± σ (y) | 62 | 8 |
| Cancer history | 161 | 19 |
| HNSCC history | 58 | 7 |
| Smoking > 10 pack-years | 797 | 94 |
| Alcohol > 3 drinks/d | 327 | 38 |
| Primary location | ||
| Oral cavity | 198 | 23 |
| Oropharynx | 292 | 34 |
| HPV+ oropharynx | 56 | 19 |
| HPV− oropharynx | 236 | 81 |
| Larynx | 205 | 24 |
| Hypopharynx | 132 | 15 |
| CUP | 25 | 3 |
| Initial 18F-FDG PET/CT | 757 | 89 |
| Stage | ||
| Early | 209 | 25 |
| I | 124 | 15 |
| II | 85 | 10 |
| Advanced | 633 | 74 |
| III | 133 | 16 |
| IV | 500 | 59 |
| Treatment | ||
| Surgery | 394 | 46 |
| Alone | 213 | 25 |
| Plus RT | 91 | 11 |
| Plus CRT | 90 | 10 |
| RT | 458 | 54 |
| Alone | 151 | 18 |
| Plus chemotherapy | 307 | 36 |
| Median year of treatment | 2016 | |
| Median follow-up (mo) | 31 | 28 |
HPV = human papilloma virus; CUP = carcinoma unknown primary; RT = radiotherapy; CRT = chemoradiotherapy.