Categories and Grades of AEs
| AE category | All grades | Severe |
|---|---|---|
| Joint reaction | ||
| Pain | 9 (16.4%) | 0 (0.0%) |
| Inflammation | 7 (12.7%) | 3 (5.5%) |
| Swelling | 6 (10.9%) | 0 (0.0%) |
| Effusion | 4 (7.3%) | 1 (1.8%) |
| Stiffness | 1 (1.8%) | 0 (0.0%) |
| Septic arthritis | 1 (1.8%) | 1 (1.8%) |
| Skin reaction | ||
| Cutaneous necrosis | 2 (0.6%) | 1 (1.8%) |
| Skin hematoma | 2 (0.6%) | 0 (0.0%) |
| Systemic reaction | ||
| Flushing | 16 (4.4%) | 0 (0.0%) |
| Fever and chills | 2 (0.6%) | 0 (0.0%) |
| Lymphadenopathy | 2 (0.6%) | 1 (1.8%) |
| Nausea | 1 (0.3%) | 0 (0.0%) |
| Palpitations | 1 (0.3%) | 0 (0.0%) |
| Medication error | 1 (0.3%) | 1 (1.8%) |
Data are number followed by percentage in parentheses. Total AEs = 55.