Brain [18F]FDG PET/MRI Parameters
| Modality | Parameter | Specification |
|---|---|---|
| [18F]FDG PET | Image protocol | 30-min static acquisition |
| Image plane | Axial | |
| Slice thickness (mm) | 2.78 | |
| Field of view (cm) | 60 | |
| Matrix size (mm) | 192 × 192 | |
| Reconstruction algorithm | Time of flight (28 subsets, 8 iterations) | |
| Glucose uptake (mg/dL) | 85.9 ± 10.16 (mean ± SD) | |
| Dose (MBq/kg) | 176.49 ± 42.55 (mean ± SD) | |
| Uptake time (min) | 43.50 ± 6.67 (mean ± SD) | |
| MRI* | 3D inversion recovery fast SPGR | |
| Image plane | Axial | |
| Slice thickness (mm) | 1 | |
| Field of view (cm) | 27 | |
| Matrix size (mm) | 256 × 256 | |
| Echo time (ms) | 3.1 | |
| Repetition time (ms) | 7,664 | |
| Flip angle | 11° | |
| Number of excitations | 1.00 | |
| 2D diffusion-weighted imaging† | ||
| Image plane | Axial | |
| Slice thickness (mm) | 5 | |
| Field of view (cm) | 24 | |
| Matrix size (mm) | 128 × 128 | |
| Echo time (ms) | 76.5 | |
| Repetition time (ms) | 5,000 | |
| Flip angle | 90° | |
| Number of excitations | 3.00 | |
| 3D arterial spin labeling† | ||
| Image plane | Axial | |
| Slice thickness (mm) | 4 | |
| Field of view (cm) | 24 | |
| Matrix size (mm) | 512 × 8 | |
| Echo time (ms) | 10.7 | |
| Repetition time (ms) | 4,854 | |
| Flip angle | 111° | |
| Number of excitations | 3.00 |
↵* 3D T2 fluid-attenuated inversion recovery and 3D multiple-echo gradient-echo (QSM/R2*) sequences were also acquired.
↵† Diffusion-weighted images were acquired with 2 diffusion weightings (b = 0 and 1,000 s/mm2). Apparent diffusion coefficient maps were automatically generated by software. Postprocessed arterial spin labeling imaging was performed by automated reconstruction script that sent CBF images directly to PACS.