TABLE 4.

Variation in Laboratory Parameters Between First Injection and Month 3 and Then 12 Months After Last Injection

Blood count parametersnBefore first injectionMonth 3 after last injectionPnBefore first injectionMonth 12 after last injectionP
GFR (mL/min/1.73 m2)3172.1 (15)72.5 (17.3)0.9212370.4 (13.9)76 (18.1)0.247
Hemoglobin (g/dL)3213.4 (1.3)12.4 (1.4)0.009*2413.2 (1.2)12.5 (1.7)0.095
Leukocytes (×109/L)326.5 (2.2)4.1 (1.2)<0.001*235.9 (1.9)4.3 (1.2)0.001*
Lymphocytes (×109/L)321.5 (0.5)0.8 (0.3)<0.001*241.5 (0.5)0.9 (0.3)<0.001*
Platelets (×109/L)31218 (68)162.5 (51.1)<0.001*24216.1 (68)185.5 (69.1)0.128
  • * P < 0.05.

  • GFR = glomerular filtration rate.

  • Data are means with SD in parentheses. P values were determined by Student t test.