Summary of Representative Oncologic Studies with FAPI PET/CT in China
| Tumor type | FAPI agent(s) | Study | Year | No. of patients |
|---|---|---|---|---|
| Head and neck squamous cell carcinoma, oral squamous cell carcinoma | 68Ga-FAPI-04 | Jiang et al. (17) | 2023 | 77 |
| Chen et al. (18) | 2022 | 36 | ||
| Head and neck cancer of unknown primary origin | 68Ga-FAPI-04 | Gu et al. (19) | 2022 | 18 |
| Nasopharyngeal carcinoma | 68Ga-FAPI-04 | Zhao et al. (20) | 2021 | 45 |
| Metastatic thyroid cancer | 68Ga-FAPI-04 | Fu et al. (21) | 2022 | 35 |
| Breast cancer | 68Ga-FAPI-04 | Zheng et al. (22) | 2023 | 34 |
| Lung cancer | 68Ga-FAPI-04 and 18F-FAPI-04 | Wang et al. (23) | 2022 | 34 |
| Zhou et al. (24) | 2022 | 74 | ||
| Wei et al. (25) | 2023 | 68 | ||
| Gastrointestinal cancer, including esophageal cancer, gastric cancer, colorectal cancers, liver cancer, biliary tract cancer, and pancreatic cancer | 68Ga-FAPI-04 and 18F-FAPI-74 | Liu et al. (26) | 2022 | 35 |
| Lin et al. (27) | 2022 | 56 | ||
| Pang et al. (28) | 2021 | 35 | ||
| Guo et al. (29) | 2021 | 34 | ||
| Lan et al. (30) | 2022 | 18 | ||
| Chen et al. (31) | 2023 | 34 | ||
| Xu et al. (32) | 2023 | 112 | ||
| Shi et al. (33) | 2021 | 17 | ||
| Zhang et al. (34) | 2022 | 30 | ||
| Qin et al. (35) | 2022 | 20 | ||
| Recurrent soft-tissue sarcoma | 68Ga-FAPI-04 | Gu et al. (36) | 2022 | 45 |
| Gastrointestinal stromal tumors | 18F-FAPI-42 | Wu et al. (37) | 2022 | 35 |
| Lymphoma | 68Ga-FAPI-04 | Chen et al. (38) | 2023 | 186 |