Patient | [177Lu]Lu-DOTATOC, 1 cycle* | [177Lu]Lu-DOTA-JR11, 1 cycle† | 2–3 cycles† | ||||||
---|---|---|---|---|---|---|---|---|---|
Meningioma dose (Gy/cycle) | Red marrow dose (Gy/cycle) | T/BM | T/K | Meningioma dose (Gy/cycle) | Red marrow dose (Gy/cycle) | T/BM ratio | T/K ratio | Meningioma dose (Gy) | |
1 | 0.8 | 0.05 | 16 | 0.6 | 4.7 | 0.16 | 30 | 3.0 | 9.5 |
2 | 1.9 | 0.10 | 19 | 0.6 | 8.4 | 0.31 | 27 | 1.8 | 15.3 |
3 | 4.4 | 0.15 | 28 | 1.5 | 14.5 | 0.27 | 54 | 4.6 | 32.3 |
4 | 5.0 | 0.17 | 30 | 0.9 | 15.0 | 0.39 | 38 | 2.5 | 43.4 |
5 | 10.2 | 0.13 | 78 | 4.0 | 22.7 | 0.34 | 66 | 8.1 | 57.7 |
6 | 2.5 | 0.08 | 29 | 1.0 | 7.1 | 0.24 | 30 | 2.0 | 13.5 |
Median | 3.4 | 0.11 | 29 | 1.0 | 11.5 | 0.29 | 34 | 2.8 | 23.8 |
Range | 0.8–10.2 | 0.05–0.17 | 16–78 | 0.6–4.0 | 4.7–22.7 | 0.16–0.39 | 25–66 | 1.8–8.1 | 9.5–57.7 |