TABLE 3.

Survival Analyses with Kaplan–Meier Estimate of OS and C-Index

	Targeted therapy				Immunochemotherapy				Immunotherapy
Feature	Cutoff	P	Short-OS	C-index	Cutoff	P	Short-OS	C-index	Cutoff	P	Short-OS	C-index
SUV_min	1.4	0.030^*	−	0.499	5.2	0.031^*	−	0.468	5.4	0.004^*	+	0.488
SUV_max	10.5	0.007^*	+	0.577	9.1	0.230		0.460	18.2	0.110		0.517
SUV_peak	9.1	0.023^*	+	0.571	12.9	0.230		0.462	11.9	0.190		0.520
SUV_mean	6.0	0.019^*	+	0.563	8.4	0.068		0.471	12.4	0.004^*	+	0.472
NHOC_max	0.435	0.290		0.477	0.608	0.076		0.540	0.793	0.007^*	+	0.581
NHOC_peak	0.521	0.220		0.496	0.475	0.150		0.500	0.502	0.005^*	+	0.614
NHOP_max	0.238	0.024^*	−	0.572	0.115	0.180		0.510	0.361	0.002^*	−	0.541
NHOP_peak	0.238	0.008^*	−	0.540	0.192	0.043^*	+	0.449	0.468	0.013^*	−	0.586
MTV (cm3)	55.7	0.029^*	+	0.529	21.4	0.006^*	+	0.592	21.0	0.003^*	+	0.624
Total lesion glycolysis	84.5	0.170		0.542	53.9	0.014^*	+	0.577	193.6	0.002^*	+	0.616
Sphericity	0.784	0.095		0.502	0.721	0.017^*	−	0.546	0.830	<0.001^*	−	0.690
Joint entropy log10	3.725	0.140		0.532	3.695	0.007^*	+	0.607	3.665	0.068		0.538
Inverse difference moment	0.04	0.030^*	+	0.488	0.036	0.022^*	+	0.455	0.039	0.025^*	+	0.421
Short run emphasis	0.99	0.071		0.480	0.993	0.015^*	−	0.449	0.991	0.024^*	−	0.433
Long run emphasis	1.04	0.035^*	+	0.486	1.026	0.015^*	+	0.459	1.034	0.024^*	+	0.431
Low gray-level zone emphasis	0.003	0.011^*	−	0.563	0.004	0.150		0.529	0.004	<0.001^*	−	0.594
High gray-level zone emphasis	6183	0.042^*	+	0.570	5776	0.034^*	−	0.433	6695	0.013^*	−	0.406

↵* P < 0.05 (log-rank test).
+ or − = higher or lower than cutoff feature value associated with poor survival.