Data for 38 Patients in Whom RP Developed
| cCRT end (mo) | Durvalumab start (mo) | CTCAE grade | RP treatment course | Persistent RP symptoms at 3 mo | Rechallenged with durvalumab |
|---|---|---|---|---|---|
| 1.3 | 0.8 | 3 | Hospitalized, oxygen, steroid taper | No | No |
| 1.4 | 0.1 | 2 | Steroid taper and antibiotics | No | Yes |
| 1.5 | 0.1 | 3 | Hospitalized, oxygen, steroid taper | Yes, remains on steroids | No |
| 1.6 | 0.4 | 2 | Steroid taper | Yes, remains on steroids | No |
| 1.7 | 1.0 | 3 | Hospitalized, oxygen, steroid taper | No | No |
| 2.0 | 0.3 | 2 | Steroid taper and antibiotics | Yes, remains on steroids | No |
| 2.2 | 1.1 | 3 | Hospitalized, oxygen, steroid taper | Yes, remains on steroids | No |
| 2.2 | 1.8 | 2 | Steroid taper and antibiotics | No | Yes |
| 2.3 | 0.5 | 2 | Steroid taper | No | No |
| 2.3 | 0.9 | 2 | Steroid taper | No | No |
| 2.5 | 0.9 | 2 | Steroid taper and antibiotics | No | No |
| 2.5 | 1.0 | 2 | Steroid taper | Yes, remains on steroids | No |
| 2.7 | 1.3 | 3 | Hospitalized, oxygen, steroid taper | Yes, remains on steroids | No |
| 3.0 | 2.1 | 3 | Hospitalized, steroid taper | Yes, remain on steroids | No |
| 3.2 | 2.5 | 3 | Steroid taper and antibiotics | Yes, remains on steroids, in pulmonary rehab | No |
| 3.3 | 1.6 | 2 | Steroid taper and antibiotics | Yes, remains on steroids | No |
| 3.3 | 2.4 | 2 | Steroid taper and antibiotics | No | No |
| 3.3 | 2.6 | 2 | Steroid taper and antibiotics | Yes, remains on steroids | Yes |
| 3.4 | 2.8 | 2 | Steroid taper and antibiotics | No | No |
| 3.5 | 2.8 | 3 | Steroid taper, supplemental oxygen | No | No |
| 3.7 | 1.9 | 2 | Steroid taper | No | No |
| 3.8 | 2.3 | 2 | Steroid taper | No | Yes |
| 3.8 | 2.5 | 3 | Hospitalized, oxygen, steroid taper | Yes, remains on steroids | No |
| 3.9 | 1.5 | 3 | Hospitalized, oxygen, steroid taper | No | No |
| 3.9 | 2.3 | 3 | Hospitalized, oxygen, steroid taper | No | No |
| 4.5 | 3.0 | 2 | Steroid taper | Yes, remains on steroids | No |
| 4.5 | 3.9 | 3 | Hospitalized, oxygen, steroid taper | Yes, remains on steroids and oxygen | No |
| 4.8 | 3.0 | 2 | Steroid taper | No | Yes |
| 5.7 | 4.8 | 2 | Steroid taper | No | No |
| 5.9 | 4.5 | 2 | Steroid taper and antibiotics | No | No |
| 5.9 | 4.6 | 2 | Steroid taper | No | No |
| 6.5 | 5.3 | 3 | Hospitalized, oxygen, steroid taper | Yes, remains on steroids | No |
| 6.8 | 4.9 | 2 | Steroid taper | No | No |
| 8.0 | 6.4 | 2 | Steroid taper and antibiotics | No | No |
| 8.4 | 7.8 | 2 | Steroid taper | No | No |
| 8.7 | 6.0 | 2 | Steroid taper | No | No |
| 9.0 | 8.1 | 2 | Steroid taper | No | No |
CTCAE = Common Terminology Criteria for Adverse Events.