TABLE 1.

Pharmacokinetics of [67Cu]Cu-EB-TATE in Healthy Female BALB/c Mice

Pharmacokinetic parameterData
Area under curve (%IA⋅h/mL)634.9 ± 6.9
Distribution t1/2 (h)0.6 ± 0.1
Clearance t1/2 (h)33.5 ± 5.2
Elimination constant (h−1)0.13 ± 0.01
Volume at steady-state (mL)6.9 ± 1.1
Clearance rate (mL/h)0.16 ± 0.00
  • Data are mean ± SD. Mice were injected with 3.86 ± 0.16 MBq (0.32 ± 0.013 nmol) of [67Cu]Cu-EB-TATE, and values were obtained from %IA/mL and time (h).