TABLE 3.

Comparison of Diagnostic Efficacy Between ⁶⁸Ga-FAPI and ¹⁸F-FDG PET (Per-Patient and Per-Region Analysis) for Tumors in Which ⁶⁸Ga-FAPI Was Comparable to ¹⁸F-FDG PET

Tumor entity	n	Stratification	PET-positive/total	Sensitivity	Specificity	PPV	NPV	Accuracy
⁶⁸Ga-FAPI PET
Breast	16	Per-patient	15/16	100 (78.2–100)	100 (2.5–100)	100	100	100 (79.4–100)
		Per-region	28/47	96.6 (82.2–100)	100 (81.5–100)	100	94.7 (72.4–99.2)	97.9 (88.7–100)
Head and neck	10	Per-patient	10/10	100 (66.4–100)	0 (0–97.5)	90 (90)	—	90.0 (55.5–99.8)
		Per-region	17/31	93.8 (69.8–99.8)	86.7 (59.5–98.3)	88.2 (67.2–96.5)	92.9 (65.9–98.9)	90.3 (74.3–98)
¹⁸F-FDG PET
Breast	16	Per-patient	15/16	100 (78.2–100)	100 (2.5–100)	100	100	100 (79.4–100)
		Per-region	28/47	100 (88.1–100)	100 (81.5–100)	100	100	100 (92.5–100)
Head and neck	10	Per-patient	10/10	100 (66.4–100)	—	90 (90)	—	90.0 (55.5–99.8)
		Per-region	18/31	100 (79.4–100)	86.7 (59.5–98.3)	88.9 (68.8–96.7)	100	93.6 (78.6–99.2)

Data in parentheses are 95% CI.