TABLE 3.

Peroperative γ-Probe Detection (In Vivo and Ex Vivo) and Characteristics of RGS-Target Lesions

Probe-positive and resected (n = 29)Probe-negative
CharacteristicResected (n = 14)Not resected* (n = 6)
LoS of lesion on 18F-PSMA PET
 515 (52%)1 (7%)3 (50%)
 49 (31%)4 (29%)0 (0%)
 35 (17%)9 (64%)3 (50%)
Location on 18F-PSMA PET/CT
 Obturator fossa13 (45%)2 (14%)0 (0%)
 External iliac11 (38%)6 (43%)0 (0%)
 Internal iliac3 (10%)1 (7%)5 (83%)
 Common iliac0 (0%)5 (36%)0 (0%)
 Pararectal and presacral2 (7%)0 (0%)1 (17%)
Histopathology
 Number of LNMs28 (97%)2 (14%)
 Size (mm)7.9 (0.8–20.0)1.8 (0.6–3.0)
 Strong PSMA expression26 (93%)0 (0%)
 Moderate PSMA expression2 (7%)1 (50%)
 Mild PSMA expression0 (0%)1 (50%)
 No PSMA expression0 (0%)0 (0%)
  • * Still present and suggestive on postoperative 18F-PSMA PET/CT.

  • LoS = level of suspicion.

  • Qualitative data are number and percentage; continuous data are mean and range.