Safety of 177Lu-DOTATATE PRRT, n = 52
| Characteristic | Data |
|---|---|
| Reason for early discontinuation of PRRT | |
| General health deterioration | 2 (4) |
| Toxicity | 4 (8) |
| Cholestasis | 1 (2) |
| Cytopenia | 1 (2) |
| Renal insufficiency | 2 (4) |
| Unknown | 3 (6) |
| Occurrence of gastrointestinal complications during PRRT | 4* (8) |
| Bowel obstruction | 1 (2) |
| Abdominal pain | 2 (4) |
| Diarrhea because of mesenteric ischemia | 1 (2) |
| Emesis | 1 (2) |
| Patients receiving short course of corticosteroid therapy | 2 (4) |
| Occurrence of long-term gastrointestinal complications | 6* (12) |
| Bowel obstruction | 3 (6) |
| Abdominal pain | 3 (6) |
| Constipation | 2 (4) |
| Perforation | 1 (2) |
| Mesenteric ischemia | 1 (2) |
| Cause of death in affected patients | |
| MM-related | 2 (4) |
| Occlusive syndrome with digestive perforation | 1 (2) |
| Missing data | 1 (2) |
| NET-related but non–MM-related | 7 (13) |
| Altered general condition with cachexia | 4 (8) |
| Missing data | 3 (6) |
| Non–NET-related | 3 (6) |
| Unknown | 2 (4) |
↵* One patient presented with both gastrointestinal complications during PRRT and long-term gastrointestinal complications.
Data are number and percentage.