Association Between Relative Change in 68Ga-DOTATATE PET/CT Parameters After C1 from Baseline and Morphologic Lesion Outcome
Parameter | Response | Lesions (n) | Median | IQR | P* | Spearman ρ | P† |
---|---|---|---|---|---|---|---|
SUVmax | R | 19 | −23% | −33% to 0% | 0.48 | ||
NR | 59 | −16% | −33% to 0% | ||||
SUVmean | R | 19 | −21% | −39% to 3% | 0.29 | ||
NR | 59 | −15% | −29% to 5% | ||||
Tumor-to-spleen ratio | R | 14 | −32% | −41% to −8% | 0.91 | ||
NR | 54 | −30% | −50% to −12% | ||||
Tumor-to-blood ratio | R | 19 | −18% | −35% to 3% | 0.44 | ||
NR | 59 | −16% | −31% to 19% | ||||
SSTR TV | R | 19 | −9% | −36% to 20% | 0.05 | 0.27 (95% CI, 0.05 to 0.47) | 0.01 |
NR | 59 | 11% | −8% to 27% | ||||
Total lesion SSTR expression | R | 19 | −27% | −46% to −3% | 0.01 | 0.32 (95% CI, 0.11 to 0.51) | 0.004 |
NR | 59 | −6% | −24% to 11% |