TABLE 1.

Absorbed Doses per Unit Activity per Cycle

	Cycle 1^*		Cycles 2–6^*
Organ or tissue	Mean	SD	Mean	SD
Lacrimal glands	2.1 (1.2–3.2)	0.47	1.8 (0.70–3.9)	0.61
Salivary glands	0.63 (0.22–1.5)	0.36	0.63 (0.23–1.4)	0.30
Left colon	0.58 (0.33–1.0)	0.14	0.58 (0.32–0.73)	0.11
Rectum	0.56 (0.32–1.1)	0.14	0.55 (0.31–0.70)	0.10
Kidneys	0.43 (0.22–0.83)	0.16	0.44 (0.17–1.0)	0.21
Right colon	0.32 (0.18–0.60)	0.08	0.31 (0.18–0.40)	0.06
Urinary bladder wall	0.32 (0.29–0.43)	0.03	0.33 (0.29–0.43)	0.03
Thyroid	0.26 (0.09–1.69)	0.37	0.21 (0.06–1.6)	0.25
Heart wall	0.17 (0.03–0.52)	0.12	0.15 (0.05–0.37)	0.08
Lungs	0.11 (0.03–0.57)	0.11	0.06 (0.02–0.17)	0.03
Liver	0.090 (0.043–0.220)	0.044	0.11 (0.037–0.26)	0.054
Small intestine	0.071 (0.043–0.220)	0.031	0.065 (0.043–0.083)	0.010
Spleen	0.067 (0.031–0.140)	0.027	0.095 (0.028–0.32)	0.056
Osteogenic cells	0.036 (0.02–0.170)	0.028	0.030 (0.016–0.062)	0.009
Red marrow	0.035 (0.020–0.13)	0.020	0.031 (0.021–0.051)	0.007
Adrenal glands	0.033 (0.016–0.15)	0.025	0.028 (0.014–0.060)	0.009
Gallbladder wall	0.028 (0.013–0.15)	0.026	0.023 (0.012–0.055)	0.008
Pancreas	0.027 (0.012–0.15)	0.026	0.021 (0.008–0.051)	0.008
Prostate	0.027 (0.013–0.15)	0.026	0.021 (0.007–0.050)	0.008
Esophagus	0.025 (0.010–0.15)	0.026	0.019 (0.006–0.050)	0.008
Stomach wall	0.025 (0.011–0.15)	0.026	0.019 (0.006–0.050)	0.008
Thymus	0.025 (0.010–0.15)	0.026	0.018 (0.004–0.049)	0.008
Testes	0.023 (0.010–0.14)	0.025	0.017 (0.003–0.046)	0.008
Eyes	0.022 (0.009–0.14)	0.024	0.016 (0.003–0.045)	0.008
Brain	0.007 (0.002–0.025)	0.005	0.006 (0.003–0.028)	0.003
Whole body	0.037 (0.019–0.170)	0.027	0.031 (0.018–0.065)	0.009

↵* Dosimetry data were available for 29 patients at cycle 1, 21 patients at cycles 2 and 3, 19 patients at cycle 4, 13 patients at cycle 5, and 10 patients at cycle 6.
Bold font indicates organs considered to be at particular risk of radiotoxicity. Data are Gy/GBq.