TABLE 2.

Efficacy of 68Ga-Pentixafor PET/CT Visual Analysis in Diagnosing Surgically Eligible PA Patients and Comparison with Adrenal CT and AVS in Patients with Pathology and Postoperative Follow-up

ModalityTPTNFPFNSensitivitySpecificityAccuracyPPVNPV
Both CT and PET/CT*
 Adrenal CT55671776.4% (65.4%–84.7%)46.2% (23.3%–70.9%)71.8% (62.2%–81.3%)88.7% (78.5%–94.4%)26.1% (12.5%–46.5%)
 PET/CT7081692.1% (86.0%–98.2%)88.9% (68.3%–100%)91.8% (85.9%–97.6%)98.6% (95.9%–100%)57.1% (31.2%–83.1%)
Both AVS and PET/CT
 AVS1022376.9% (49.7%–91.8%)50.0% (15.0%–85.0%)70.6% (48.9%–92.2%)83.3% (55.2%–95.3%)40.0% (11.8%–77.0%)
 PET/CT1131284.6% (57.8%–95.7%)75.0% (30.0%–95.4%)82.4% (64.2%–100%)91.7% (76.0%–100%)60.0% (23.1%–88.2%)
  • * n = 85.

  • n = 17.

  • TP = true-positive; TN = true-negative; FP = false-positive; FN = false-negative; PPV = positive prediction value; NPV = negative prediction value.

  • Data in parentheses are 95% CIs.