TABLE 2.

Summary of Dosimetry Results

PatientMean ADRPT (Gy/GBq)*Mean AD delivered by SBRT (Gy)Mean total from RPT (Gy)Mean BED from SBRT (Gy)Mean total BED (Gy)§Maximum total BED (Gy)§
1 [1]3.727.753113160185
1 [2]NA27.9NA114NANA
2 [3]5.028.173116186217
3 [4]2.928.841121158171
4 [5]7.728.4114118219258
4 [6]5.127.975114187209
4 [7]3.728.254116158179
5 [8]1.128.316117124138
6 [9]2.126.731106131141
Median3.7 (2.4)28.1 (0.4)58 (37)116 (3)159 (35)182 (48)
  • * As calculated from first-cycle serial SPECT/CT imaging.

  • Mean within gross tumor volume.

  • Total dose from both cycles, assuming second cycle contributes 90% of dose from first cycle. Mean within VOI is as defined on PSMA PET/CT.

  • § Mean BED from RPT and SBRT within VOI as defined on PSMA PET/CT. Mean BED from RPT and SBRT within gross tumor volume was approximately 5% lower.

  • NA = not available.

  • Numbers in brackets are number of lesions; numbers in parentheses are IQR. Lesion 2 was not within SPECT field of view, assuming α/β ratio of 3 Gy.