Summary of Dosimetry Results
Patient | Mean ADRPT (Gy/GBq)* | Mean AD delivered by SBRT (Gy)† | Mean total from RPT (Gy)‡ | Mean BED from SBRT (Gy)† | Mean total BED (Gy)§ | Maximum total BED (Gy)§ |
---|---|---|---|---|---|---|
1 [1] | 3.7 | 27.7 | 53 | 113 | 160 | 185 |
1 [2] | NA | 27.9 | NA | 114 | NA | NA |
2 [3] | 5.0 | 28.1 | 73 | 116 | 186 | 217 |
3 [4] | 2.9 | 28.8 | 41 | 121 | 158 | 171 |
4 [5] | 7.7 | 28.4 | 114 | 118 | 219 | 258 |
4 [6] | 5.1 | 27.9 | 75 | 114 | 187 | 209 |
4 [7] | 3.7 | 28.2 | 54 | 116 | 158 | 179 |
5 [8] | 1.1 | 28.3 | 16 | 117 | 124 | 138 |
6 [9] | 2.1 | 26.7 | 31 | 106 | 131 | 141 |
Median | 3.7 (2.4) | 28.1 (0.4) | 58 (37) | 116 (3) | 159 (35) | 182 (48) |
↵* As calculated from first-cycle serial SPECT/CT imaging.
↵† Mean within gross tumor volume.
↵‡ Total dose from both cycles, assuming second cycle contributes 90% of dose from first cycle. Mean within VOI is as defined on PSMA PET/CT.
↵§ Mean BED from RPT and SBRT within VOI as defined on PSMA PET/CT. Mean BED from RPT and SBRT within gross tumor volume was approximately 5% lower.
NA = not available.
Numbers in brackets are number of lesions; numbers in parentheses are IQR. Lesion 2 was not within SPECT field of view, assuming α/β ratio of 3 Gy.