TABLE 2.

PSMA Uptake Levels of Normal Organs According to Antihormonal Treatment Status

Variable	Control (n = 56)	ADT (n = 56)	Difference	P
Kidney SUV_mean^*^†	29.5 ± 7.2; 95% CI, 27.57–31.42; range, 16.59–52.12	21.61 ± 8.1; 95% CI, 19.44–23.78; range, 5.18–37.36	Δyes − no = −7.89; 95% CI, −10.73 to −5.04	<0.001
Kidney SUV_peak^*	54.76 ± 14.29; 95% CI, 50.94–58.59; range, 26.65–93.75	40.64 ± 16.49; 95% CI, 36.23–45.06; range, 6.82–77.99	Δyes − no = −14.12; 95% CI, −19.85 to −8.39	<0.001
Liver SUV_mean^‡	4.8 ± 1.31; 95% CI, 4.45–5.15; range, 2.15–8.63	4.44 ± 1.65; 95% CI, 3.99–4.88; range, 0.92–10.39	ΔADT − control = −0.14; 95% CI, −0.86 to 0.10	0.12
Liver SUV_peak^‡	18.06 ± 14.75; 95% CI, 14.11–22.01; range, 3.81–55.8	11.18 ± 8.97; 95% CI, 8.78–13.58; range, 1.19–37.64	ΔADT − control = −2.3; 95% CI, −5.72 to −0.93	0.003
Spleen SUV_mean^‡	6.08 ± 2.04; 95% CI, 5.53–6.62; range, 2.55–11.59	5.86 ± 2.42; 95% CI, 5.21–6.51; range, 0.782–14.56	Δyes − no = −0.49; 95% CI, −1.5 to 0.99	0.46
Spleen SUV_peak^‡	14.76 ± 11.15; 95% CI, 11.78–17.75; range, 4.81–53.79	11.56 ± 9.61; 95% CI, 8.99–14.13; range, 1.14–52.34	ΔADT − control = −1.27; 95% CI, −3.61 to −0.16	0.033
Salivary gland SUV_mean^‡^§	11.34 ± 2.69; 95% CI, 10.62–12.06; range, 4.41–17.05	9.93 ± 3.17; 95% CI, 9.07–10.8; range, 1.18–18.02	ΔADT − control = −1.04; 95% CI, −2.48 to −0.13	0.027
Salivary gland SUV_peak^*	20.0 ± 5.02; 95% CI, 18.65–21.34; range, 7.53–34.76	16.69 ± 5.61; 95% CI, 15.16–18.22; range, 1.7–30.42	ΔADT − control = −3.31; 95% CI, −5.3 to −1.31	0.001

↵* t test data as mean ± SD.
↵† Two patients underwent unilateral nephrectomy.
↵‡ Mann–Whitney test data as median and IQR.
↵§ Two scans (2/56, 4%) did not include salivary glands in field of view.