TABLE 3.

Multivariate Regression Analysis of Relationship Between Renal, Hepatic, Splenic, and Salivary Gland PSMA Uptake and Explanatory Variables MTV, Glomerular Filtration Rate, and ADT Status

Predicted endpointVariableOdds ratioP
Kidney SUVmean
Intercept17.78; 9.28 to 26.27<0.0001
MTV (cm3)−0.218; −0.495 to 0.05850.121
GFR (mL/min)0.156; 0.0531 to 0.2590.0034
ADT (0 = no, 1 = yes)−7.95; −11.06 to −4.84<0.0001
Liver SUVpeak
Intercept10.94; −1.06 to 22.940.0735
MTV (cm3)0.0389; −0.301 to 0.3790.821
GFR (mL/min)0.09; −0.0606 to 0.2410.238
ADT (0 = no, 1 = yes)−7.85; −11.78 to −3.91<0.0001
Spleen SUVpeak
Intercept6.36; −5.73 to 18.450.299
MTV (cm3)0.295; −0.114 to 0.7040.156
GFR (mL/min)0.104; −0.0615 to 0.270.214
ADT (0 = no, 1 = yes)−5.83; −9.95 to −1.70.006
SM SUVmean
Intercept12.2; 8.67 to 15.73<0.0001
MTV (cm3)−0.0679; −0.183 to 0.04720.244
GFR (mL/min)−0.00771; −0.0506 to 0.03520.722
ADT (0 = no, 1 = yes)−1.47; −2.76 to −0.1670.0274
  • GFR = glomerular filtration rate; SM = Submandibular gland.

  • Odds ratio is followed by 95% CI.