Binding Characteristics of 99mTc-EDDA/HYNIC-iPSMA and 99mTc-PSMA-GCK01
| Substance | Uptake (%AD/106 cells) | Unspecific uptake (%AD/106 cells) | Specific uptake (%AD/106 cells) | Ki (nm) |
|---|---|---|---|---|
| 99mTc-EDDA/HYNIC-iPSMA (reference compound) | 20.3 ± 0.3 | 1.64 ± 0.07 | 18.7 ± 0.3 | 38 |
| 99mTc-PSMA-GCK01 | 19.6 ± 4.8 | 1.2 ± 0.6 | 18.4 ± 4.2 | 26 |
%AD = Applied dose; Ki = inhibition constant.