TABLE 3.

ROC Subanalysis of 6-Month Toxicity for Patients Who Underwent Partial Liver Treatment (CTCAE Grade 3+ Hyperbilirubinemia, 4 Positive and 74 Negative)

ParameterAD-WNTLTHRV20V30V40AD-20AD-30
AUC0.5780.5910.5340.5460.5420.5200.588
P value0.6290.4520.8680.8110.8180.079<0.001
P value vs AD-WNTLT*0.900.410.450.300.720.95
Cutoff58.7 Gy33.8%6%6%5%0 Gy0 Gy
  • * P value of ROC comparison between each voxel-based parameter and AD-WNTLT (multicompartment parameter); cutoff was determined by Youden index.

  • HR = hepatic reserve, that is, liver volume not treated by radioembolization.