TABLE 1.

Adult Effective Dose Coefficients and Relative Differences Compared Among MIRDcalc, IDAC-Dose, and ICRP Publication 128

RadiopharmaceuticalEffective dose coefficient (mSv/MBq)
MIRDcalcIDAC-DoseOLINDAICRP 128FormulaFormulaFormulaFormulaFormulaFormula
111In-octreotide5.49E−025.38E−025.89E−025.40E−02−2.0−2.0%7.07.3%−1.7−1.6%
123I-ioflupane2.50E−022.36E−022.16E−022.50E−02−5.8−5.6%−15−14%0.000.00%
123I-NaI capsules (high thyroid uptake)2.45E−012.45E−012.77E−013.00E−010.000.00%1213%2022%
123I-NaI capsules (thyroid blocked)3.04E−023.02E−022.04E−023.70E−02−0.66−0.7%−40−33%2022%
131I-NaI capsules (high thyroid uptake)2.17E+012.16E+012.64E+012.90E+01−0.46−0.50%2022%2934%
131I-NaI (thyroid blocked)2.10E−012.08E−011.55E−012.80E−01−0.96−1.0%−30−26%2933%
133Xe gas1.99E−041.64E−041.86E−041.80E−04−19−18%−6.8−6.5%−10−9.5%
133Xe gas (rebreathing for 10 min)1.27E−031.21E−031.11E−031.10E−03−4.8−4.7%−13−13%−14−13%
14C-urea, Heliobacter positive8.68E−027.75E−028.93E−028.10E−02−11−11%2.82.9%−6.9−6.7%
14C-urea, normal case2.42E−022.16E−022.93E−023.10E−02−11−11%1921%2528%
18F-FDG1.67E−021.61E−021.92E−021.90E−02−3.7−3.6%1415%1314%
18F-NaF1.30E−021.28E−021.65E−021.70E−02−1.6−1.5%2427%2731%
201Tl-TlCl1.13E−011.09E−018.47E−021.40E−01−3.6−3.5%−29−25%2124%
67Ga-citrate9.43E−028.97E−028.72E−021.00E−01−5.0−4.9%−7.8−7.5%5.96.0%
82Rb-chloride1.05E−031.00E−037.77E−041.10E−03−4.9−4.8%−30−26%4.74.8%
99mTc-DMSA7.02E−036.92E−037.24E−038.80E−03−1.4−1.4%3.13.1%2325%
99mTc-DTPA3.37E−033.26E−034.57E−034.90E−03−3.3−3.3%3036%3745%
99mTc-ECD5.56E−035.52E−035.08E−037.70E−03−0.72−0.70%−9.0−8.6%3339%
99mTc-iminodiacetic acid derivatives9.44E−039.55E−033.84E−031.60E−021.21.2%−90−59%5370%
99mTc-macroaggregated albumin1.40E−021.15E−021.37E−021.10E−02−20−18%−2.2−2.1%−24−21%
99mTc-MAG34.12E−034.09E−036.38E−037.00E−03−0.73−0.70%4455%5370%
99mTc-sestamibi, exercise6.19E−036.03E−033.74E−037.90E−03−2.6−2.6%−50−40%2428%
99mTc-sestamibi, rest7.09E−036.89E−034.64E−039.00E−03−2.9−2.8%−42−35%2427%
99mTc-HMPAO8.35E−037.99E−037.10E−039.30E−03−4.4−4.3%−16−15%1111%
99mTc sulfur colloid1.10E−021.09E−021.11E−029.10E−03−0.91−0.90%0.900.90%−19−17%
99mTc-pertechnetate, with blocking agent4.07E−033.78E−034.47E−034.60E−03−7.4−7.1%9.49.8%1213%
99mTc-pertechnetate, no blocking agent9.99E−039.87E−034.24E−031.30E−02−1.2−1.2%−86−58%2630%
99mTc-MDP4.32E−034.25E−035.10E−034.90E−03−1.6−1.6%1718%1313%
99mTc-tetrofosmin, exercise5.63E−035.37E−034.51E−036.90E−03−4.7−4.6%−22−20%2023%
99mTc-tetrofosmin, rest6.09E−035.89E−034.56E−038.00E−03−3.3−3.3%−29−25%2731%
  • Fluorodeoxyglucose (FDG), dimercaptosuccinic acid (DMSA), diethylenetriaminepentaacetic acid (DTPA), ethylenedicysteine diester (ECD), mercaptoacetyltriglycine (MAG3), hexamethylpropyleneamine oxime (HMPAO), methyl diphosphonate (MDP).