TABLE 3.

Kinetic Parameters of ⁶⁸Ga-FAPI-04 Using 2T4K and Multigraphical Analysis Based on 60-Minute Acquisition

ROI	2T4K					Logan (V_t [mL/cm³])	Patlak (K_i [mL/cm³/min])	RE plot with the Patlak plot (V_t [mL/cm³])	RE (V_t [mL/cm³])
ROI	K₁ (mL/cm³/min)	k₂ (1/min)	k₃ (1/min)	k₄ (1/min)	V_t (mL/cm³)	Logan (V_t [mL/cm³])	Patlak (K_i [mL/cm³/min])	RE plot with the Patlak plot (V_t [mL/cm³])	RE (V_t [mL/cm³])
Heart	0.427 (0.139)	1.403 (0.387)	0.050 (0.044)	0.088 (0.065)	0.442 (0.078)	0.540 (0.095)	0.0001 (0.0007)	0.542 (0.095)	0.540 (0.090)
Lung	0.048 (0.085)	0.392 (0.579)	0.071 (0.093)	0.060 (0.051)	0.138 (0.029)	0.205 (0.061)	−0.0005 (0.0006)	0.205 (0.061)	0.208 (0.065)
Liver	0.446 (0.140)	1.019 (0.467)	0.038 (0.045)	0.022 (0.015)	1.151 (0.622)	1.012 (0.583)	0.0032 (0.0024)	1.019 (0.584)	0.951 (0.542)
Spleen	1.488 (0.581)	2.978 (1.364)	0.043 (0.019)	0.071 (0.057)	0.991 (0.373)	0.995 (0.369)	0.0029 (0.0024)	0.999 (0.372)	0.948 (0.320)
Kidney	1.235 (0.694)	3.243 (2.585)	0.588 (0.835)	0.280 (0.256)	1.215 (0.396)	1.188 (0.274)	0.0006 (0.0024)	1.190 (0.275)	1.176 (0.272)
Pancreas	0.863 (0.569)	1.349 (0.830)	0.151 (0.097)	0.065 (0.045)	2.282 (1.331)	2.253 (1.354)	−0.0004 (0.0115)	2.294 (1.342)	2.226 (1.495)
Thyroid	1.196 (0.430)	2.510 (1.566)	0.060 (0.061)	0.047 (0.026)	1.281 (0.642)	1.223 (0.553)	0.0030 (0.0019)	1.232 (0.555)	1.185 (0.540)
Parotid gland	0.185 (0.067)	0.481 (0.303)	0.167 (0.260)	0.060 (0.039)	1.402 (0.393)	1.329 (0.403)	0.0023 (0.0050)	1.345 (0.402)	1.267 (0.392)
Submandibular gland	0.395 (0.099)	0.520 (0.197)	0.074 (0.067)	0.072 (0.056)	1.684 (0.559)	1.612 (0.573)	−0.0019 (0.0072)	1.616 (0.573)	1.624 (0.630)
Bone	0.008 (0.004)	0.083 (0.046)	0.041 (0.080)	0.139 (0.215)	0.152 (0.079)	0.126 (0.055)	0.0001 (0.0008)	0.132 (0.064)	0.118 (0.036)
Muscle	0.038 (0.072)	0.259 (0.260)	0.199 (0.190)	0.088 (0.184)	0.603 (0.510)	0.640 (0.545)	0.0038 (0.0033)	0.659 (0.541)	0.464 (0.391)
PT	0.285 (0.118)	0.325 (0.360)	0.377 (0.394)	0.039 (0.031)	10.502 (2.972)	10.042 (2.849)	0.0661 (0.0180)	10.351 (2.740)	6.098 (1.941)
LNM	0.328 (0.290)	0.900 (1.174)	0.299 (0.330)	0.028 (0.019)	6.181 (3.556)	4.236 (3.170)	0.0310 (0.0208)	4.963 (3.435)	3.248 (2.085)
OM	0.203 (0.130)	0.252 (0.313)	0.133 (0.125)	0.020 (0.009)	7.275 (2.947)	5.457 (2.296)	0.0351 (0.0306)	6.564 (2.757)	3.711 (1.103)

ROI = region of interest.